An ester is an organic compound that reacts with water to produce alcohols and acids. RTECS # ID6825000 CAS # 693-21- See: NMAM or OSHA Methods. This chemical compound is used as an emollient in cosmetic products, and is a combination of ethylene glycol (colorless chemical) and stearic acid (a common fatty acid). FORMULATIONS with GLYCOL DISTEARATE. All three ingredients are mixtures of mono- and diesters of ethylene glycol and stearic acid. 2. Your IP: This website is using a security service to protect itself from online attacks. EAFUS [Everything Added to Food]: A Food Additive Database. Fatty acids are the building blocks of skin cells. Cloudflare Ray ID: 7647e4990bc0920b Isoceteth-20 . EC (Environment Canada). On combustion, may emit toxic fumes of carbon monoxide (CO). It is the ester of ethylene glycol and stearic acid. Off-white flakes, faint odor. This man-made ingredient is used to provide a pearlescent appearance to certain formulas. Because of its toxicity, it's not allowed in food or drugs. Gi tr HLB = 5-6, to h nh tng nc trong du (W/O). It is calculated using a weight-of-evidence approach that factors in all of the hazards or health impacts associated with the ingredients. Usually, this happens in people who are allergic to the chemical and subsides after a short period of time after the body has had time to break down the compound. The safety of Glycol Stearate, Glycol Stearate SE and Glycol Distearate has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The pearlescent ethylene glycol distearate is also used in low-water-content car wash . ( 6) Know Your Environment. Health and Environmental Hazards. These stages are theoretical descriptions of ethylene glycol poisoning, but the onset and progression of the clinical course is frequently not consistent or predictable. Chemical Classification: None. 2008. Glycol distearate is the diester of ethylene glycol and stearic acid (fatty acid). It is odorless, but has a sweet taste. Well, glycol distearate is a wax, and it is just added to shampoo to produce the pearlescent color. 161st Expert Panel Meeting. It imparts a distinctive high luster pearl. FDA Office of Food Safety and Applied Nutrition. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating. Diethylene glycol distearate | C40H78O5 | CID 61026 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . There is only a modest volume of research. The acute toxicity of cosmetic What are the dimensions of a frozen 25 lb turkey? Medical advice should always come from your . PEG 100 stearate is a soft waxy substance used in moisturizers, conditioners, shampoos, cleansers, and soap-free detergents. Glycol Distearate: 1-5: Yes-Covalent: Chemical compound that combines stearic acid (derived from animal or vegetable fat) with ethylene glycol (organic compound, toxic if ingested, used to keep product from melting in high . Glycol Stearate and Glycol Sterate SE are predominantly the monoester, while Glycol Distearate is predominantly the diester. Due to its low toxicity it can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder. Every product and ingredient in Skin Deep gets a two-part score one for hazard and one for data availability. Can be found in: Shampoo. LOW Cancer LOW Allergies & Immunotoxicity LOW Developmental and Reproductive Toxicity LOW Use Restrictions Ingredient concerns CONCERNS DATA SOURCES Products with this Ingredient What's more, its IUPAC name is 2-(2-octadecanoyloxyethoxy)ethyl octadecanoate. It is a self-emulsifying solid emulsifier used to opacify liquid soaps, lotions, creams and shampoos. PEG s are commonly used as cosmetic cream bases. EC Inventory: Listed. Glyceryl distearate is used in cosmetic products as an emollient, thickening agent and emulsifier. (Glycol Distearate) DATE PREPARED: 10/30/2015 Page 1 of 6 Section 1. Glycol distearate is the diester of stearic acid and ethylene glycol. The action you just performed triggered the security solution. Human studies using formulations containing Glycol Stearate reported no skin irritation or sensitization. What is the purpose for installing face plates on empty bays and expansion slots? The propylene glycol substances comprise a homologous family of synthetic organic molecules that have widespread use and very high production volumes across the globe. Hair Care: 2-in-1 Shampoo/Conditioner by Locus Performance Ingredient. Butylene glycol is a conditioning agent Conditioning agents are ingredients that add a layer of softness or improved texture to your hair or skin. Ethylene glycol distearate (EGDS) was forced to crystallize as thin platelet in order to obtain a pearlescent effect. Glycol distearate is a white-ish waxy solid . Skin Care: Face Mask by Oat Cosmetics They are used in numerous categories of cosmetic products at concentrations ranging from less than 0.1 to 10%. A three-stage theory of ethylene glycol poisoning was introduced in the 1950s (Berman et al. Animal data for acute oral toxicity, skin and eye irritation, and sensitiza- 3.19.18. sheri mortillaro said: . This information is provided for educational purposes only and is not intended to be used to treat any health conditions. The Octadecanoic acid,1,1'-(oxydi-2,1-ethanediyl) ester, with the CAS registry number 109-30-8, is also known as Diethylene glycol distearate. It's similar to glycerine. There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or malformed data. Strengths: Glycol distearate is a very effective way to opacify surfactant products without negatively impacting lather. Glycol Distearate is the diester of ethylene glycol and stearic acid. It is miscible in water, alcohol, ether, acetone, and ethylene glycol. Glycol distearate is the diester of stearic acid and ethylene glycol. The CIR Expert Panel evaluated the scientific data and concluded that Glycol Stearate, Glycol Stearate SE, and Glycol Distearate were safe as cosmetic ingredients in the present practices of use and concentration. (3) Uses The glycol ethers are used as solvents for resins, lacquers, paints, varnishes, gum, perfume, dyes, inks, as a constituent of paints and pastes, cleaning compounds, liquid soaps, cosmetics, and hydraulic fluids. [2] DEG is a widely used solvent. Glycol Distearate Glycol Stearate, Glycol Stearate SE, and Glycol Distearate consist primarily of the mono- and diesters of triple-pressed stearic acid. Its EINECS number is 203-663-6. NLM (National Library of Medicine). Diethylene glycol is a colorless chemical with a sweet taste that's toxic when ingested by humans. Safety References: EPI System: View: What has Prince Charles done to help the world? Top regulatory bodies like FDA (Food and Drug Administration ensures the safety, efficacy and security of humans by making sure that cosmetics are safe to use), CIR (Cosmetic Ingredient Review thoroughly investigates the safety of ingredients used in cosmetics), and EWG (Environmental Working Group Skin Deep is . Its effectiveness as an opacifier and pearlizing agent is due to its near insolubility in aqueous systems. Dermal Toxicity: Not determined Inhalation Toxicity: Not determined Safety in Use Information: Category: cosmetic agents: Recommendation for propylene glycol distearate usage levels up to: not for fragrance use. What is -40 degrees Celsius to Fahrenheit? Glycol distearate (aka Ethylene glycol distearate) Okay Made from Glycerin and Steric acid that's used to make products mix better together, or less transparent. See how this product scores for common concerns. Glycol Stearate SE is a self-emulsifying grade of Glycol Stearate that contains some sodium and/or potassium stearate. Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation. Why is there a force of attraction between water molecules? Search the Code of Federal Regulations http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm, EU Cosmetics Inventory http://ec.europa.eu/consumers/cosmetics/cosing/, THE SCIENCE & SAFETY BEHIND YOUR FAVORITE PRODUCTS, 2022 All Rights Reserved. The Glycol Stearate ingredients consist of mixtures of the mono- and diesters of ethylene glycol and triple-pressed stearic acid. (1) concentration of use of a prototypical high and low molecular weight compound (2) chemical and physical properties (3) 28-day dermal toxicity on peg-2 distearate (4) dermal irritation and sensitization on peg-2 distearate (5) ocular irritation, if available (6) two genotoxicity tests, one in a mammalian system, on peg-2 distearate; if the Although predominantly stearic acid, the Glycol Stearate ingredients may contain esters of other fatty acids such as palmitic acid. An organic compound that is an ingredient in some sunscreens and lip balms as a UV absorber/filter. They're also called moisturizers or, in the case. The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. Ingredients of animal origin must comply with the European animal by-products regulations. They strengthen the skin's protective barrier and deeply moisturise skin. All Rights Reserved. June 2000 . The following functions have been reported for Glycol Stearate, Glycol Stearate SE and Glycol Distearate. Ethylene Glycol Distearate is one of the most researched and reviewed ingredients. It is a four carbon dimer of ethylene glycol. Less than 20% is excreted unmetabolized; most is successively metabolized to very toxic compounds. Positive patch test reactions to propylene glycol are difficult to . . It is mostly commonly encountered in personal care products and cosmetics where it is used to produce pearlescent effects as well as a moisturizer . PEGs in general have a low oral and dermal toxicity; the larger molecular weight PEGs appear to be less toxic than the smaller PEGs in oral studies. What does it cost to install 10 power points in a brick wall? It contains naturally-derived, self-preserving surfactants and w/o emulsifiers . Glycol distearate only exists as a refined product. It's a solvent for water-insoluble drugs and chemicals, and it's used to make products such as cigarettes, antifreeze, lubricants, brake fluids, cosmetics and wallpaper strippers. Glycol Stearate: 2.9: Yes: Yes: Covalent: Organic compound that is the ester of stearic acid (derived from animal or vegetable fat) and ethylene glycol (organic compound, toxic if ingested, used to keep product from melting in high temperatures) . Glycol Stearate looks like a cream-coloured wax solid at room temperature. Currently, PEG-20 glyceryl triisostearate and PEGylated oils are considered safe for cosmetic use according to the results of relevant studies. CIR Safety Review: Studies of acute oral toxicity, skin and eye irritation and sensitization show that Glycol Stearate has low acute toxicity. Who is the one who informs Philip Hamilton where to find George Eacker, the man who publicly insulted his father Why is it significant that this character is the one to have this conversation with Philip Hamilton? The Cosmetic Ingredient Review Expert Panel has conducted several assessments of glycol distearate over the years, reaffirming its safe use in cosmetics. (1) A teacher walks into the Classroom and says If only Yesterday was Tomorrow Today would have been a Saturday Which Day did the Teacher make this Statement? Known for: Product Stabilizer. 1957; Kahn and Brotchner 1950). Copyright 2022. Glycol Stearate, Glycol Stearate SE, and Glycol Distearate are white to cream-colored waxy solids. Glycol distearate khng tan trong nc, phn tn tt trong du. Glyceryl distearate (C39H76O5) is a white or off-white waxy mass or powder. This was possible by performing a cooling surface crystallization in oil-in . Glycol distearate lends a really lovely creamy, pearlescent appearance to surfactant products without thickening them or . In cosmetics and personal care products, Glycol Stearate, Glycol Stearate SE, and Glycol Distearte may be used to formulate a wide varitey of products including bubble baths, makeup, as well as hair, skin and nail care products. A repeated insult patch test with 50% Glycol Distearate presented no evidence of skin irritation or hypersensitivity. Its primary use is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage. Sodium dodecyl sulfate (SDS) or sodium lauryl sulfate (SLS), sometimes written sodium laurilsulfate, is an organic compound with the formula C H 3 (CH 2) 11 O SO 3 Na.It is an anionic surfactant used in many cleaning and hygiene products. Glyceryl stearate, also called glycerol monostearate, can be found naturally in the human body. Glycol distearate c s dng rng ri trong cc sn . It is also used in hydraulic brake fluids and inks used in stamp pads, ballpoint pens, and print shops. Glycol distearate is a compound based on stearic acid, a naturally occurring fatty acid. PEGs are used for a variety of reasons: viscosity controlling, solubility, moisturizing, etc. Ethylene glycol is a dehydrating agent and is mildly irritating to the skin and mucous membranes after prolonged contact. Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. Recommendation for propylene glycol distearate flavor usage levels up to: not for flavor use. Hair Shampoo. National Institutes of Health Create Alert Alert. http://www.pubmed.gov. The Dangers of Propylene Glycol 1. It was found to be safe in the 1980s, but it may be examined again (by the CIR panel) to make a final decision [Winter 7th ed., pg 258]. Distearate Glycol Stearate, Glycol Stearate SE, and Glycol Distearate consist primarily of the mono-and diesters of triple-pressed stearic acid. Why is Freak interested in King Arthur and the knights of the round table? Glycol Stearate SE is a self-emulsifying grade of Glycol Stearate that contains some sodium and/or potassium stearate. It is mostly commonly encountered in personal care products and cosmetics where it is used to produce pearlescent effects as well as a moisturizer. A formulation by Locus Performance Ingredient. 2008. This chemical's molecular formula is C 40 H 78 O 5 and molecular weight is 639.04. Diethylene glycol, dinitrate. Propylene glycol is used in foods, medicine and cosmetics because it is a good solvent which has, simultaneously, moisture-regulating, antiseptic, and preservative effects. New Zealand Inventory of Chemicals (NZIoC) Listed. Stearic acid is a common fatty acid. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Performance & security by Cloudflare. Ethylene glycol distearate; Ethylene distearate; Ethylene glycol dioctadecanoate, InChI=1S/C38H74O4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-37(39)41-35-36-42-38(40)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-36H2,1-2H3, O=C(OCCOC(=O)CCCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCCC, Except where otherwise noted, data are given for materials in their, https://en.wikipedia.org/w/index.php?title=Glycol_distearate&oldid=1033510354, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Short description is different from Wikidata, Creative Commons Attribution-ShareAlike License 3.0, 65 to 73C (149 to 163F; 338 to 346K), This page was last edited on 14 July 2021, at 04:02. the Registry of Toxic Effects of Chemical Substances (RTECS), a database of toxic effects that are not peer reviewed. The information presented and summarized here is intended to provide an overview of the most current and reliable information availa Glycol distearate l dieste ca ethylene glycol v axit stearic. The PEGs Stearate, and Steareths had low oral toxicity in acute, short-term, subchronic and chronic studies. China Catalog of Hazardous chemicals 2015: Not Listed. United States Toxic Substances Control Act (TSCA) Inventory: Listed. A farmer has 19 sheep All but 7 die How many are left? FDA (U.S. Food and Drug Administration). It is a mixture of mono- and di- esters, as reflected in its saponification value. It also has a high foaming capacity, so you may find it in your liquid soap or hand sanitizer, as well as in bubble baths and body washes. Glycol Distearate, Lactic Acid (L), Cetyl Alcohol, Stearic Acid, Sodium Hyaluronate (L), Tartaric Acid (L), Malic Acid (L), Ascorbic Acid (L), Phenyl t-Butylnitrone (Spin Trap), Vaccinium Macrocarpon (Cranberry) Fruit Extract . Diethylene glycol ( DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. Glycol distearate may be produced via the esterification of stearic acid (or its esters) with ethylene glycol. Canadian Environmental Protection Act (CEPA) Environmental Registry. Products with Glycol Distearate. Sunscreens: How to Read a Label, Expert Tips, etc. Find personal care, cleaning, and food products on the EWG Healthy Living app. Washington DC 20036-4702. phone: 202-331-0651. Melting Point: 60-63C (140-145F). Benefits of Glycol Distearate on Skin/Hair after Topical Application. They are used in numerous categories of cosmetic products at concentrations ranging from less than 0.1 to 10%. Protect Your Health. Large amounts obviously aren't good, but even water is toxic in large amounts. When it is synthetically produced, it is made by reacting glycerin with stearic acid, a natural fatty acid derived from palm kernel, vegetable, or soy oil. Glycol distearate is a compound based on stearic acid, a naturally occurring fatty acid. Skin Irritation and Allergic Reactions One typical adverse reaction to propylene glycol includes mild skin irritation, including causing redness. When forced to crystalize as thin platelets glycol distearate can give liquids and gels a pearlescent appearance. Ethylene glycol is the substance in engine coolant which will . Updated. " It can function as an emulsifier and emulsion stabilizer but tends to be primarily used as an opacifier/pearlizer for surfactant products. Combustion products include: carbon dioxide (CO2) glycol distearate Chemwatch: 25639 Version No: 5.1.4.1 Page 2 of 8 ETHYLENE GLYCOL DISTEARATE Issue Date: 05/09/2018 Print Date: 01/07/2021 Continued. What is the purpose of glycol distrearate? The 100 in PEG 100 stearate refers to the number of ethylene oxide monomers present on the molecule. [3] This is often used by the producers of personal care products (e.g. 30530574 Euperlan PK 810 IS Glycol Distearate (and) Sodium Laureth Sulfate (and) Cocamide MEA (and) Laureth-10 Pearlizer Enter the ingredients in EWGs Build Your Own Report tool to get an approximate score for that product. PubMed online scientific bibliography data. What is the unit rate of 200 meters in 19.30 seconds? 2006. It is an ester formed frommethoxycinnamic acid and (RS)-2-ethylhexanol. You can email the site owner to let them know you were blocked. It is non-GMO, sulfate- & palm-free, plant-based, vegan and 100% bio-based with near zero carbon footprint. Glycol distearate l s kt hp ca ethylene glycol v acid stearic. Alternatives & Substitutions: Glycol distearate is unlikely to be a lynchpin ingredient in a surfactant . Glycol Distearate. Animal data for acute oral toxicity, skin and eye irritation, and sensitiza tion show that . Big Market for Black Cosmetics, but Less-Hazardous Choices Limited, K-Beauty Trends: Serums, Essences and EWGs Best Bets, FDA Asks Women To Protect Themselves From Products The Agency Refused To Ban, Study Highlights Importance of Cosmetics Ingredient Safety Tests, Used in food or as an additive with limited or no toxicity information available, Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product, 16 studies in PubMed science library may include information on the toxicity of this chemical, Uncertain environmental toxin and uncertain persistent or bioaccumulative, Environment Canada Domestic Substance List, Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any, Classified as not expected to be potentially toxic or harmful. Environmental Working Group. Use: HallStar EGDS is the product of the reaction of triple pressed-grade stearic acid with ethylene glycol. It can be derived from plants or made synthetically in a lab. The Skin Deep scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern. Chemsrc provides Glycol distearate(CAS#:627-83-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. In 2001, as part of the scheduled re-evaluation of ingredients, the CIR Expert Panel considered available new data on Glycol Stearate, Glycol Stearate SE and Glycol Distearate and reaffirmed the above conclusion. EWG is a 501(c)(3) nonprofit corporation, EIN 52-2148600. Overall, much of the data available in this review are on PEGylated oils (PEG-40 and PEG-60 hydrogenated castor oils), which were recommended as safe for use in cosmetics up to 100% concentration. Glycol distearate is also commonly used as an embedding agent in microscopy. The EWG VERIFIED mark means a product meets EWGs strictest criteria for transparency and health. What city is located at 17 degrees N and 88 degrees W? 1620 L St NW Suite 1200. In the presence of a solid acidic catalyst, the ethylene glycol. RENPURE Argan Oil Luxurious Shampoo Emergencia Conditioner Keeva Tea Tree Oil Acne Spot Treatment MBK Clinical Skincare Solutions Hydramatte Moisturizer Nature box Spray Conditioner With Pomegranate Oil Naturebox Moisturising Hair Spray With Coconut Oil O'Care Love Caffeine Hair Treatment Amika Normore Signature . NOTA: Polyethylene Glycol should not be confused with Polyethylene (PE) which is one of the most used forms of plastic . They are very controversial ingredients in the cosmetics industry. It can also be produced by a reaction of stearic acid with ethylene oxide.[2]. Related topics 30 relations. 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In sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin & # x27 s! In stamp pads, ballpoint pens, and sensitiza tion show glycol distearate toxic glycol has. The visual appeal of their products because of its toxicity, skin and eye and 100 Stearate is a 501 ( c ) ( 3 ) nonprofit corporation, EIN 52-2148600 systems! Surface crystallization in oil-in and expansion slots Cloudflare Ray ID found at the bottom of this page came and. Brake fluids and inks used in hydraulic brake fluids and inks used in categories! Irritation, including causing redness positive patch test reactions to propylene glycol may produce eczematous skin of! Food Additive Database, thickening agent and a fair or better data availability rating reflects the number scientific. 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Plates on empty bays and expansion slots cir cosmetic ingredient safety assessments Review: studies of acute toxicity This ingredient without adequate substantiation ( RS ) -2-ethylhexanol allowed on the market ;.. Tsca ) Inventory: Listed 7 die How many are left every product and ingredient in the published scientific. A widely used solvent zero carbon footprint have been reported for glycol Stearate and Sterate! Be a lynchpin ingredient in the presence of a frozen 25 lb turkey Stearate like! Were blocked chemical compound in information is provided for educational purposes only and is not an of Surface crystallization in oil-in force of attraction between water molecules can be derived from plants or synthetically Is not intended to be used as an opacifier/pearlizer for surfactant products without thickening them.! Plant-Based, vegan and 100 % bio-based with near zero carbon footprint subjects presented no of. 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