These companies took a further step by publishing the first list of discharge targets to guide environmental risk assessments for the manufacture of antibiotics. This research will focus on preventing infections caused by multi-drug resistant organisms in high-risk patients in facilities such as intensive care units, wound infections with biofilm complications, post-discharge methicillin-resistant Staphylococcus aureus patients, and impact of environmental (e.g., room) cleaning protocols. Opals drug, BDM-I, is a small molecule that has shown in vitro activity against many serious human pathogens including six identified by the CDC in the 2013 Antibiotic Resistance Threats Report. As the nations largest nonprofit health system, Ascension is committed to working on improving antimicrobial use and the cleanliness of the healthcare environment to combat the threat of antimicrobial resistance (AMR) in its healthcare facilities. Pison will collaborate with product manufacturers to communicate antimicrobial resistance results to the public from its research and development and Pisons mission to prevent bacterial growth on highly-contaminated surfaces. The First Arabian Drug Information Center (FADIC), a professional health care organization in the Middle East, commits to maintaining the appropriate use of antibiotics through antimicrobial stewardship education and by providing certification in antimicrobial stewardship training programs for pharmacists, physicians, nurses, and other healthcare professionals. AMS works hand-in-hand with infection prevention and control strategies Ref:20, Antimicrobial Stewardship (AMS) Safety, Quality and Equity dimensions Does your organisation keep up to date with the latest evidence and strive to innovate and implement that standard of care? As a 2018-2019 Science Envoy, Dr. Michael Osterholm, Ph.D., MPH will work to support key priorities including addressing the emergence and spread of drug-resistant disease globally. Wellcome Trust(United Kingdom) Resistance to antimicrobial agents has become a major source of morbidity and mortality worldwide. Antimicrob Resist Infect Control. 2016 Dec;219:993-997. doi: 10.1016/j.envpol.2016.04.099. Company progress will be assessed on an annual basis. Additionally, SHARPS will ensure stewardship activities are implemented in 50% of its hospitals caring for hospitalized children by the end of 2021. Antimicrobials - including antibiotics, antivirals, antifungals and antiparasitics - are medicines used to prevent and treat infections in humans, animals and plants. The Alliance companies will continue to take action and share their experiences to reduce environmental impact from the production of antibiotics. MSH will work with technical experts to ensure WASH is accurately and adequately represented in global health security, including antibiotic resistance. Ascension(Missouri, U.S.) ECDC launched an online resources directory to support EU member states and institutions in developing guidelines for the prevention and control of antimicrobial resistance and healthcare-associated infections. Premier will work with more than 500 members in its Hospital Improvement Innovation Network (HIIN), funded by Centers for Medicare & Medicaid Services, to provide education, technical assistance, and evidence-based strategies to implement all seven of the CDCs Core Elements of Hospital Antibiotic Stewardship Programs and reduce the rate of healthcare-associated C. difficile by 20 percent by March 2019. The Milken Institute is a nonprofit, nonpartisan think tank determined to increase global prosperity. Findings reveal widespread availability of antimicrobials without prescription in the country including rise in its irrational use across sectors and consequent contamination of environment and spread of resistance. Montana is implementing statewide interventions including clinical pathways for infections such as C. difficile, and systemic approaches based upon CDCs Core Elements of Antibiotic Stewardship. NCDC also commits to the development and distribution of a national toolkit for antimicrobial stewardship in healthcare institutions, advocacy for the creation of hospital multi-disciplinary antimicrobial stewardship committees in at least 85 percent of all federal institutions, and the implementation of a national infection prevention and control program using a participatory quality development approach (PQDA) in at least 85 percent of federal healthcare institutions. Clostridium difficile is recognized as one of the leading causes of diarrhea and is responsible for almost all cases of pseudomembranous colitis. BD is mobilizing the Antimicrobial Resistance Fighter Coalition campaign to improve awareness; will support surveillance and research by collating, in specific projects, MedMinedTM data with the CDC to help better understand resistance in the U.S. and track regional differences in important resistant pathogens and antimicrobial use; is advancing infection prevention practices by introducing innovative infection control solutions and deploying training programs in collaboration with international organizations and professional societies; and is helping extend the useful life of existing medications through stewardship training and innovative integration of diagnostic testing, microbiology results and medication management workflows. Success will be measured by a reduction of 35% in AMR infections over time. West Virginia Bureau for Public Health commits to conducting onsite visits to acute, long-term care, and outpatient facilities to assess infection control and antibiotic stewardship practices while providing guidance to strengthen programs. The Massachusetts Department of Public Health (Massachusetts, U.S.) In 2016, NIH/NIAID published a paper in the Journal of the American Medical Association reinforcing the need for novel approaches to combat antibiotic resistance. The Washington State Department of Health commits to addressing the threat of antibiotic resistance through the Combating Antibiotic Resistant Bacteria Initiative to stop the emergence and transmission of antibiotic-resistant organisms. With more than 91,000 members, AVMAs efforts will support common understanding of the critical role of effective antibiotic stewardship in combating the development of antibiotic resistance through: ongoing collaboration with the Food and Drug Administration to achieve enhanced veterinary oversight of antibiotic use; education of the veterinary profession on antibiotic stewardship; assistance with enhanced surveillance of antibiotic use in animals; support for research; and more active engagement with international stakeholders. AAHA will also have educational tracks at numerous veterinary conferences in 2019 to educate and inform veterinary colleagues about the new ICPB guidelines to promote the highest standard of care for animals. Montefiore Medical Center (New York, U.S.) Progress will be measured through a series of surveys, gap analysis, and working with the facilities to address identified gaps. Additionally, it will respond to and contain antibiotic-resistant threats by working with statewide partners, its Quality Innovation Network-Quality Improvement Organization, hospital associations, healthcare facilities, and various health department programs. Alaska Department of Health and Social Services (Alaska, U.S.) J. Arthur Dosher Memorial Hospital, a critical access hospital in North Carolina, commits to reducing the inappropriate use of fluoroquinolones for urinary tract infections, community-acquired pneumonia, and skin infections by educating hospitalists and emergency department physicians. Across its hundreds of providers, Doctor on Demand will lower unnecessary antibiotic prescribing by 20 percent by December 2019 for acute upper respiratory infections including bronchitis, sinusitis and pharyngitis and require two hours of continuing education training for all providers. FDA continues collaboration with CDC on the Antibiotic Resistance Isolate Bank. volunteer activity guide. Summary. The Nevada Division of Public and Behavioral Health commits to addressing the threat of antibiotic resistance through its Healthcare-Associated Infection (HAI) Program. PMC The Bill & Melinda Gates Foundation has always prioritized the fight against drug resistance in our infectious disease work, from TB, HIV, diarrheal diseases and malaria to, increasingly, pneumonia and neonatal sepsis. Nebraska Department of Health and Human Services (Nebraska, U.S.) National Neisseria Network National Notifiable Diseases Surveillance System OrgTRx, AURA 2017 Key Findings Antibiotic use in the Community Australia has very high usage of antibiotics in the community - 46% of individual Australians received an antibiotic in 2015 Antibiotics were most commonly dispensed for very young people and older people, with: 51% of those aged 04 years 60% of those aged 65 years or over, and 76% of those aged 85 years or over being supplied at least one antibiotic in 2015 30% of MedicineInsight patients (just under 1million people) were prescribed systemic antibiotics between 1 January and 31 December 2015. PowerPoint Presentation Author: Anita Muys Created Date: 2016 Oct 15;63(8):1087-1093. doi: 10.1093/cid/ciw475. You want to know more about it ? The Wisconsin Department of Health Services (DHS) Division of Public Health commits to addressing the threat of antibiotic resistance through education and enhanced surveillance. Their solutions include water and environmental control, and safe drinking water. Second, using machine learning (a subset of artificial intelligence) to identify genetic markers for sequence-based prediction of antimicrobial susceptibility. Trends project that by 2050, Asia will have the highest number of deaths attributable to antimicrobial resistance (AMR) on earth. government site. Appropriateness: was it a good choice? NAPHS commits to improving antibiotic use and combating emerging resistance strains in Egyptian healthcare settings by contributing to the development of institutional antibiotic policies. Saving Lives, Protecting People, Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Healthcare Quality Promotion (DHQP), Actions to Fight Antimicrobial Resistance, What CDC Is Doing: Investments & U.S. Action, CDC Invests in Multi-Country Projects to Help Stop Spread of Resistance, Pilot to Test for Drug-resistant Gonorrhea in Emergency Departments, CDCs Priority to Address Health Equity Issues, Protecting Patients and Healthcare Personnel from COVID-19, Experts Discuss Addressing AR After COVID-19, CDC Partners Estimate Healthcare Cost of Antimicrobial resistant Infections, Tailoring Antibiotic Treatment For Patients with Cystic Fibrosis, Tracking Antimicrobial Resistance in Kenya and Senegal, CDC Core Elements to Help Resource-limited Settings Improve Antibiotic Use, Antimicrobial Resistance: A Global Threat, Combating Antimicrobial Resistance in Vietnam, Pilot Program Accelerates Antibiotic Testing, Stop Spread of Unusual Antimicrobial Resistance, New CDC Network Established as Fungal Threat Emerges, Improving Antibiotic Prescribing with Rapid Diagnostics and Education, CDC and Partners Tackle Drug-Resistant TB in India, U.S. Department of Health & Human Services. 5D Health Protection Group Ltd (United Kingdom) The Department of Health and Environmental Control from South Carolina commits to addressing the threat of antibiotic resistance by requiring hospitals and laboratories to report multi-drug resistant organisms; testing for drug sensitivities for carbapenem-resistant Enterobacterales, carbapenem-resistant Pseudomonas aeruginosa, Candida auris, vancomycin-intermediate/resistant Staphylococcus Aureus (VISA/VRSA), and drug susceptibility test genotyping for resistant tuberculosis through our state laboratory; conducting outreach to sentinel hospital labs highlighting CDCs Antibiotic Resistance Laboratory Network testing in 2019; and planning annual regional and statewide meetings to improve antibiotic stewardship in 2019. C Diff Foundation commits to continuing to recognize the serious disease burden and significant economic impact that antimicrobial resistance (AMR) and healthcare-associated infections place on patients, their families, in communities, and the health care systems throughout the world. Global Health Council (GHC), a global membership organization supporting and connecting global health advocates worldwide, commits to advocating with the U.S. government and global organizations for policy and programs that lead to improvements in safe drinking water, sanitation, and hygiene (WASH) in healthcare facilities. Opal Biosciences, an Australian preclinical-stage biotechnology company focused on the development of novel treatments for antibiotic-resistant or hard-to-treat infections, commits to continuing to develop urgently needed new anti-infectives for life-threatening and hard-to-treat infections. Waterfowl are a major source of Salmonella transmission, but there are few systematic studies on Salmonella prevalence in waterfowl species. It is the third joint inter-agency report on integrated analysis of antimicrobial agent consumption and occurrence of antimicrobial resistance in bacteria from humans and food-producing animals (JIACRA), prepared by the three agencies at the request of the European Commission (EC). Reducing these infections can improve patient outcomes and slow antibiotic resistance. The Antimicrobial Stewardship Collaborative of South Carolina (ASC-SC), the coordinator of antimicrobial stewardship and infection prevention efforts across the state, commits to collaborating with its partner facilities to advance local antimicrobial stewardship programs by implementing CDCs Core Elements of Antimicrobial Stewardship. This means previously effective antimicrobial drugs (e.g. AHCA strongly supports antibiotic stewardship as a national priority. USP will work within the USP-APEC Center of Excellence to train regulators and industry on quality assurance practices that help combat AMR. These reports will also contain urgent care facilities and their affiliated prescribers, to enable detailed analysis of provider prescribing patterns by CDC and the states across the range of acute care settings. The American Association of Swine Veterinarians (AASV), a professional association with more than 1,500 members in more than 40 countries, commits to promoting antibiotic stewardship among swine veterinarians by providing resources with information on appropriate antibiotic use. What tools are used (e.g.. National Antimicrobial Prescribing Survey [NAPS], jurisdictional audit tools) If participating in NAPS, insert your healthcare facilities results here: Consider results compared to national results Time series data how the your facilitys NAPS results have contributed to your AMS program. IRC will continue to support capacity development of civil society organizations at the country level to influence budgets and policies on WASH in healthcare facilities, specifically Ministries of Health. . American Urological Association (Maryland, U.S.) The American Academy of Family Physicians (AAFP), one of the nations largest medical organizations with 134,600 members, commits to educating its membership on the importance of antibiotic stewardship. Clin Infect Dis. Efforts will focus on collaborating with key partnersincluding professional boards, the state hygienic laboratory, and state universitiesto continue containment efforts and identify new targets for public health prevention and interventions. Arkansas Department of Health (Arkansas, U.S.) Express Scripts (Missouri, U.S.) International Confederation of Midwives (Netherlands) In order to protect patients and communities from resistance, CDC will continue to leverage its unique expertise to: collaborate with other countries to prevent and contain the global spread of resistance threats; partner with states and countries to improve antibiotic use; enhance detection and tracking in the U.S., including scaling up cuttingedge laboratory technology through CDCs Antibiotic Resistance Laboratory Network; pilot new and innovative approaches to combat resistance domestically and globally; and share isolates via the CDC and FDA Antibiotic Resistance Isolate Bank to inform the development of new drugs and diagnostics. The Program in Global Surgery and Social Change commits to promoting policies to strengthen data collection of surgical infections, to reduce the rate of surgical infections, and to encourage responsible antibiotic use. Nearly 700,000 people around the world die every year due to drug- resistant infections. CARB-X will invest $80 million globally by December 2019 to support more than 40 antibiotic resistance product developers worldwide, including at least 10 new classes against Gram-negative bacteria, five new diagnostics, and 10 new non-traditional alternatives or vaccines. New Hampshire Department of Health and Human Services (New Hampshire, U.S.) Antibiotic Awareness Week 2018. The U.S.India Strategic Partnership Forum (USISPF) is a non-profit organization that seeks to strengthen the bilateral relationship between India and the U.S. Recognizing that antimicrobial resistance (AMR) is a critical issue for both countries, USISPF commits to: working with members and other relevant stakeholders to identify new business or public-private partnership models that can improve access to antibiotics and other antimicrobial products; helping to develop corporate social responsibility (CSR) initiatives on AMR to leverage Indias two percent CSR mandate for greater impact; providing guidance on best practices for preventing the release of antibiotics into the environment, and encouraging members to review their manufacturing and supply chains based on these standards; advocating for good stewardship of antibiotics in healthcare and agriculture; and working with the Department of Biotechnology and other partners to provide institutional support to biotechnology startups working on AMR. The products will include antimicrobial laundry additives, antimicrobial surface cleaning wipes, and antimicrobial wound care dressings, and will launch in 2019-2021. Scientists find levels of resistance all over the country and map them to determine where the sources are located. Antibiotic stewardship education is provided through its ongoing partnership with MHA and MSQIN/QIO. Texas Department of State Health Services (Texas, U.S.) IRC (Netherlands) U.S. Department of Health and Human Services Office of Global Affairs (Washington, D.C., U.S.) FADIC will also provide a roadmap for applying antimicrobial stewardship in multiple healthcare settings, including acute-care hospitals, long-term care facilities, ambulatory care settings, and community pharmacies to provide an evidence-based practice. contents. Program staff work with state and community partners to provide education on how to improve antibiotic use and prescribing and identify and educate those who overprescribe to decrease the inappropriate use of antibiotics in Nevada. The department will also continue to support antimicrobial stewardship by offering resources and technical assistance to healthcare facilities and prescribers to ensure antibiotics are appropriately used to treat infections. Next Science, a company focusing on the disruption and disinfection of biofilms (microbial cells that adhere to each other on a surface), commits to the development of topical, non-antibiotic treatments that are effective against biofilms. An official website of the United States government. The Antibiotic Resistance Action Center (ARAC) at the Milken Institute School of Public Health, George Washington University, commits to advancing knowledge of how antibiotic use in food animals impacts human health and to improving antibiotic prescribing in the urgent care sector. HealthforAnimals, the global association representing animal medicine companies and regional/national industry associations, commits to addressing antibiotic resistance by supporting One Health approaches that work across human and animal health; encouraging responsible antibiotic use of antibiotics; promoting disease prevention and increased access to products and expertise for farmers, veterinarians, and pet owners; investing in development of products for prevention and treatment such as vaccines, diagnostics, nutritional products, and more; and increasing knowledge, transparency, and communication within the industry. The department coordinates a tiered, regional response to identify affected patients, provide technical assistance to facilities on infection prevention and control practices, and improve communication between facilities by reporting antimicrobial-resistant pathogens and sending automated alerts. DNV GL has also established a certification in infection prevention that includes antibiotic stewardship requirements, and encouraged all DNV GL accredited organizations to participate in the AMR Challenge. Melinta Therapeutics, Inc., a commercial-stage company developing and bringing novel antibiotics to market to treat serious bacterial infections caused by antibiotic-resistant bacteria, commits to implementing comprehensive measures and metrics within the companys commercial, manufacturing, and collaborative research initiatives to promote the responsible and sustainable use of its antibiotics as demonstrated by stewardship program implementation of early empiric therapy guidelines. The Georgia Department of Public Health (GDPH) commits to using survey data from 350 dentists in the state to improve antibiotic use in dental settings. National Association of Pediatric Nurse Practitioners (New York, U.S.) SDDOH will provide technical assistance to healthcare providers, enhance collaborative partnerships, strengthen analysis, and enhance infection control in outbreak-affected facilities. BJC HealthCare and Washington University School of Medicine will develop and implement a penicillin allergy assessment and testing protocol across all BJC facilities by the end of 2019. The American Public Health Association (APHA) commits to raising awareness through communications channels, The Nations Health, in-person events and social media among its 25,000 members of how antibiotic resistance places public health at risk, and what steps public health professionals can take to be part of the solution. 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